Steven A Porcelli Selected Research

Therapeutics

1/2022	Mycobacterium tuberculosis PPE51 Inhibits Autophagy by Suppressing Toll-Like Receptor 2-Dependent Signaling.
1/2021	Mycobacterium tuberculosis PE_PGRS20 and PE_PGRS47 Proteins Inhibit Autophagy by Interaction with Rab1A.
1/2021	Aspirin Actions in Treatment of NSAID-Exacerbated Respiratory Disease.
1/2021	Harnessing the Versatility of Invariant NKT Cells in a Stepwise Approach to Sepsis Immunotherapy.
11/2020	Identification of Autophagy-Inhibiting Factors of Mycobacterium tuberculosis by High-Throughput Loss-of-Function Screening.
1/2019	Promotion or Suppression of Murine Intestinal Polyp Development by iNKT Cell Directed Immunotherapy.
4/2009	Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors.
4/2009	A critical role for CD8 T cells in a nonhuman primate model of tuberculosis.
8/2007	Combined natural killer T-cell based immunotherapy eradicates established tumors in mice.
11/2005	NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs.

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Steven A Porcelli Research Topics

Disease

33	Tuberculosis (Tuberculoses) 01/2022 - 07/2002
23	Infections 12/2023 - 08/2003
22	Neoplasms (Cancer) 03/2024 - 07/2003
6	Communicable Diseases (Infectious Diseases) 01/2023 - 03/2004
5	Asthma (Bronchial Asthma) 01/2024 - 02/2007
4	Inflammation (Inflammations) 07/2010 - 09/2004
3	Virus Diseases (Viral Diseases) 01/2023 - 07/2004
2	Starvation 01/2021 - 04/2008
2	Sepsis (Septicemia) 01/2021 - 02/2004
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2018 - 11/2005
2	Disease Progression 02/2007 - 07/2005
2	Leprosy (Hansen's Disease) 03/2005 - 03/2004
2	Autoimmune Diseases (Autoimmune Disease) 01/2003 - 06/2002
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Rhinosinusitis 01/2021
1	Bites and Stings (Sting) 01/2021
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2021
1	Hypersensitivity (Allergy) 01/2021
1	Melanoma (Melanoma, Malignant) 01/2021
1	Nasal Polyps (Nasal Polyp) 01/2021
1	Aspirin-Induced Asthma 01/2021
1	Polyps 01/2019
1	Intestinal Polyps 01/2019
1	Zika Virus Infection 01/2018
1	Urinary Bladder Neoplasms (Bladder Cancer) 01/2017
1	Carcinoma (Carcinomatosis) 01/2017
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 02/2016
1	Malaria 09/2015
1	HIV Infections (HIV Infection) 01/2014
1	Dyslipidemias (Dyslipidemia) 09/2010

Drug/Important Bio-Agent (IBA)

28	VaccinesIBA 12/2023 - 08/2003
12	CytokinesIBA 01/2024 - 07/2004
10	Galactosylceramides (Galactocerebrosides)IBA 01/2022 - 02/2011
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2002
9	GlycolipidsIBA 01/2021 - 07/2002
9	LipidsIBA 10/2018 - 07/2002
8	AntigensIBA 01/2021 - 01/2003
6	alpha-galactosylceramideIBA 08/2007 - 07/2003
5	LigandsIBA 01/2019 - 07/2004
4	AntibodiesIBA 01/2021 - 02/2007
3	BCG Vaccine FDA Link 01/2016 - 02/2012
3	AerosolsIBA 01/2013 - 08/2003
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2010 - 03/2007
2	Ribosomal Proteins (Ribosomal Protein)IBA 12/2023 - 01/2018
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 04/2009
2	Tuberculosis VaccinesIBA 01/2021 - 04/2009
2	EpitopesIBA 01/2021 - 01/2020
2	KRN 7000 (KRN7000)IBA 12/2020 - 03/2007
2	Peptides (Polypeptides)IBA 01/2013 - 03/2005
2	Interleukin-17 (Interleukin 17)IBA 01/2013 - 07/2010
2	Interleukin-12 (IL 12)IBA 06/2008 - 10/2004
2	Mycolic Acids (Mycolic Acid)IBA 06/2008 - 03/2007
2	Interleukin-13IBA 09/2007 - 07/2004
2	T-Cell Antigen Receptors (T-Cell Receptor)IBA 04/2007 - 09/2004
2	Interleukin-4 (Interleukin 4)IBA 03/2007 - 07/2004
1	ZincIBA 12/2023
1	Subunit VaccinesIBA 01/2023
1	Arginine (L-Arginine)FDA Link 01/2021
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021
1	HaptensIBA 01/2021
1	Leucine (L-Leucine)FDA Link 01/2021
1	Methionine (L-Methionine)FDA Link 01/2021
1	ChemokinesIBA 01/2021
1	Cyclooxygenase 1IBA 01/2021
1	AmidesIBA 12/2020
1	Interleukin-2 (IL2)IBA 12/2020
1	Immunoglobulin G (IgG)IBA 01/2020
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	4-hydroxy-3-methyl-2-butenyl diphosphateIBA 01/2019
1	GlycosphingolipidsIBA 01/2019
1	C-glycosideIBA 01/2019
1	ClathrinIBA 01/2018
1	Chloroquine (Aralen)FDA LinkGeneric 01/2018
1	bafilomycin A1IBA 01/2018
1	Peptide LibraryIBA 01/2018
1	Chlorpromazine (Thorazine)FDA Link 01/2018
1	Ammonium Chloride (Sal Ammoniac)FDA Link 01/2018
1	safingol (sphinganine)IBA 01/2018
1	SugarsIBA 01/2018
1	EstersIBA 01/2018
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2018
1	MannosidesIBA 07/2017
1	Inositol (Myoinositol)IBA 07/2017
1	Immune Checkpoint InhibitorsIBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 01/2017
1	Prealbumin (Transthyretin)IBA 02/2016
1	Lipoproteins (Lipoprotein)IBA 09/2014
1	Attenuated VaccinesIBA 01/2011
1	Lysine (L-Lysine)FDA Link 01/2011
1	Interleukin-6 (Interleukin 6)IBA 07/2010
1	Interleukin-1 (Interleukin 1)IBA 07/2010
1	DPPE-PEG2000IBA 02/2010
1	Interleukin-12 Subunit p40IBA 06/2008

Therapy/Procedure

11	Therapeutics 01/2022 - 07/2005
9	Immunotherapy 03/2024 - 08/2007
1	Injections 01/2021
1	Ligation 01/2021
1	Punctures 01/2021
1	Cell- and Tissue-Based Therapy (Cell Therapy) 01/2018
1	Aftercare (After-Treatment) 01/2017